SCHEMBL6637642

SCHEMBL6637642

CCOC(=O)C(C)Oc1ccnc(Oc2cc(N=C=O)c(F)cc2Cl)n1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPOX P50336 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.33
TSHR P16473 1/20 0.33
GAA P10253 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 1/20 0.31
RXRA P19793 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2B Q13224 1/20 0.30
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6638642 0.91 MEN1 (0.37) L3MBTL1KMT2AALDH1A1MEN1SMN1; SMN2
SCHEMBL6637880 0.86 PPOX (0.37) PPOXL3MBTL1GAATDP1KMT2A
SCHEMBL6639677 0.85 PPOX (0.40) PPOXL3MBTL1TSHRGAATDP1
SCHEMBL6639776 0.84 PPOX (0.40) PPOXL3MBTL1TSHRGAATDP1
SCHEMBL10578397 0.82 PPOX (0.52) PPOXL3MBTL1TSHRGAATDP1
SCHEMBL6639174 0.81 PPOX (0.38) PPOXL3MBTL1GAATDP1KMT2A
SCHEMBL6637267 0.80 LMNA (0.38) TSHRGAAKMT2AALDH1A1SMN1; SMN2
SCHEMBL6672101 0.79 PPOX (0.36) PPOXL3MBTL1TSHRGAATDP1
SCHEMBL6640252 0.75 MEN1 (0.38) L3MBTL1TSHRGAAKMT2AALDH1A1
SCHEMBL6636961 0.74 PPOX (0.41) PPOXTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122244-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2004-09-29 EP claimed
US-6537948-B1 Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-25 US claimed
EP-1122244-A1 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-08 EP claimed