Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639776 | 0.85 | PPOX (0.40) | PPOXTSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL6637642 | 0.85 | PPOX (0.38) | PPOXTSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL6672101 | 0.80 | PPOX (0.36) | PPOXTSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL6638493 | 0.76 | BCAT1 (0.44) | PPOX | |
| SCHEMBL6638642 | 0.76 | MEN1 (0.37) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6640252 | 0.76 | MEN1 (0.38) | TSHRKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6636961 | 0.74 | PPOX (0.41) | PPOXTSHR | |
| SCHEMBL6637880 | 0.70 | PPOX (0.37) | PPOXKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6664050 | 0.70 | MEN1 (0.38) | TSHRKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6641028 | 0.70 | PPOX (0.40) | PPOXKMT2AALDH1A1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122244-B1 | Uracil compounds and their use | SUMITOMO CHEMICAL CO (JP) | 2004-09-29 | — | — | EP | disclosed |