Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298905 | 0.80 | CNR2 (0.48) | HDAC6CNR1CNR2F2 | |
| SCHEMBL14266715 | 0.80 | CNR2 (0.49) | HDAC6CNR1CNR2AGTR1AGTR2 | |
| SCHEMBL6638110 | 0.78 | CNR2 (0.42) | HDAC6CNR1CNR2RECQLTHRB | |
| SCHEMBL6299929 | 0.75 | LTB4R2 (0.44) | LTB4R2HDAC6CNR2F2 | |
| SCHEMBL6635073 | 0.73 | LTB4R2 (0.43) | LTB4R2HDAC6F2 | |
| SCHEMBL5103828 | 0.72 | AGTR1 (0.40) | CNR1CNR2F2RECQLTHRB | |
| SCHEMBL6300098 | 0.71 | AGTR1 (0.42) | F2AGTR1AGTR2 | |
| SCHEMBL6300102 | 0.70 | AGTR1 (0.39) | CNR1CNR2F2RECQLAGTR1 | |
| SCHEMBL6304436 | 0.69 | ALOX5 (0.40) | LTB4R2HDAC6CNR2 | |
| SCHEMBL6298922 | 0.69 | AGTR1 (0.38) | HDAC6F2RECQLAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165557-B1 | ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES: SELECTIVE MODULATORS OF GABAa RECEPTORS | NEUROGEN CORP (US) | 2004-09-29 | — | — | EP | claimed |