Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 3/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12945425 | 0.80 | LMNA (0.56) | ALDH1A1PTGS2PPARDMAPTLMNA | |
| SCHEMBL7476275 | 0.80 | ALDH1A1 (0.55) | ALDH1A1F2GLAHPGDMAPT | |
| SCHEMBL12476341 | 0.78 | CXCR1 (0.61) | CXCR1CXCR2SMN1; SMN2MAPTPOLB | |
| SCHEMBL6638177 | 0.78 | CXCR1 (0.55) | CXCR1CXCR2SMN1; SMN2PTGS2MAPT | |
| SCHEMBL27703439 | 0.77 | ALDH1A1 (0.42) | ALDH1A1F2GLAHPGDMAPT | |
| SCHEMBL5845815 | 0.76 | CXCR1 (0.53) | CXCR1CXCR2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2549786 | 0.76 | KDM4E (0.57) | CXCR1CXCR2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27374761 | 0.76 | L3MBTL1 (0.57) | ALDH1A1F2GLAHPGDMAPT | |
| SCHEMBL12476476 | 0.75 | CXCR1 (0.57) | CXCR1CXCR2SMN1; SMN2MAPTPOLB | |
| SCHEMBL15327912 | 0.75 | CXCR1 (0.57) | CXCR1CXCR2SMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122244-B1 | Uracil compounds and their use | SUMITOMO CHEMICAL CO (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6537948-B1 | Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-25 | — | — | US | disclosed |
| EP-1122244-A1 | Uracil compounds and their use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-08 | — | — | EP | disclosed |