Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 8/20 | 0.63 |
| ▸ | WNT3A | P56704 | 8/20 | 0.63 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29987426 | 1.00 | CTNNB1 (0.63) | CTNNB1WNT3AHTR1BMRGPRX4IDO1 | |
| SCHEMBL11243027 | 0.85 | CTNNB1 (0.59) | CTNNB1WNT3AHTR1BMRGPRX4IDO1 | |
| SCHEMBL28200508 | 0.84 | CTNNB1 (0.55) | CTNNB1WNT3AHTR1BMRGPRX4IDO1 | |
| SCHEMBL31438451 | 0.84 | HTR1B (0.57) | CTNNB1WNT3AHTR1BMRGPRX4CHRNA7 | |
| SCHEMBL879386 | 0.84 | HTR1B (0.57) | CTNNB1WNT3AHTR1BMRGPRX4CHRNA7 | |
| SCHEMBL4318315 | 0.84 | CTNNB1 (0.58) | CTNNB1WNT3AHTR1BIDO1CHRNA7 | |
| SCHEMBL1919332 | 0.83 | MRGPRX4 (0.58) | CTNNB1WNT3AMRGPRX4KMO | |
| SCHEMBL103953 | 0.82 | CTNNB1 (0.59) | CTNNB1WNT3AHTR1BIDO1CHRNA7 | |
| Hydrochloric Acid SCHEMBL6627889 | 0.82 | HTR1B (0.55) | CTNNB1WNT3AHTR1BMRGPRX4CHRNA7 | |
| SCHEMBL28431104 | 0.82 | CTNNB1 (0.59) | CTNNB1WNT3AHTR1BIDO1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 409 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707872-A | Method for amidation of carboxylic acid and continuous flow photochemistry device | 国网安徽省电力有限公司电力科学研究院 | 2025-03-28 | — | — | CN | claimed |
| CN-119504653-A | Carboxylic acid amidation method | 国网安徽省电力有限公司电力科学研究院 | 2025-02-25 | — | — | CN | claimed |
| CN-119504652-A | Method for amidating carboxylic acid and gas-liquid mixed flow photochemical device | 国网安徽省电力有限公司电力科学研究院 | 2025-02-25 | — | — | CN | claimed |
| CN-119504433-A | Carboxylic acid esterification method | 国网安徽省电力有限公司电力科学研究院 | 2025-02-25 | — | — | CN | claimed |
| CN-119504431-A | Method for esterification of carboxylic acid and continuous flow photochemistry device | 国网安徽省电力有限公司电力科学研究院 | 2025-02-25 | — | — | CN | claimed |
| CN-119504430-A | Carboxylic acid esterification method and gas-liquid mixed flow photochemical device | 国网安徽省电力有限公司电力科学研究院 | 2025-02-25 | — | — | CN | claimed |
| CN-118955549-A | Method for dehydrogenating and coupling silicon and aromatic heterocyclic compound and application thereof | 中山大学 | 2024-11-15 | — | — | CN | claimed |
| EP-3870582-B1 | 5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2023-07-19 | — | — | EP | claimed |
| CN-116429936-A | Method for detecting benzofuran-5-carboxylic acid in benzofuran-6-carboxylic acid | 四川美域高生物医药科技有限公司 | 2023-07-14 | — | — | CN | claimed |
| US-20140088105-A1 | Cyclohexyl Amide Derivatives and Their Use as CRF-1 Receptor Antagonists | NOVARTIS AG (CH) | 2014-03-27 | — | — | US | claimed |
| JP-2011529944-A | — | — | 2011-12-15 | — | — | JP | claimed |
| CN-102143940-A | Cyclohexyl amide derivatives as CRF-1 receptor antagonists and uses thereof | NOVARTIS AG | 2011-08-03 | — | — | CN | claimed |
| EP-1836163-B1 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | NOVARTIS AG (CH) | 2010-09-22 | — | — | EP | claimed |
| US-20100087427-A1 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | BREITENSTEIN WERNER | 2010-04-08 | — | — | US | claimed |
| WO-2010015655-A1 | CYCLOHEXYL AMIDE DERIVATIVES AND THEIR USE AS CRF-1 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2010-02-11 | — | — | WO | claimed |
| US-20100035898-A1 | Organic compounds | NOVARTIS AG (CH) | 2010-02-11 | — | — | US | claimed |
| CN-101522661-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (VG) | 2009-09-02 | — | — | CN | claimed |
| EP-1836163-A2 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | Novartis AG (CH) | 2007-09-26 | — | — | EP | claimed |
| EP-1754705-A2 | Antagonists for treatment of CD11/CD18 adhesion receptor mediated disorders | Genentech, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| WO-2006066896-A2 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | NOVARTIS AG (CH) | 2006-06-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035898-A1 | Organic compounds | CRH, CRHR1, CRHR2 | CTNNB1 3471/4885WNT3A 3412/4885HTR1B 47/4885 |
| US-20100087427-A1 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN | REN, ACE, PEPD | CTNNB1 4687/4885WNT3A 4038/4885HTR1B 2028/4885 |
| US-20140088105-A1 | Cyclohexyl Amide Derivatives and Their Use as CRF-1 Receptor Antagonists | CRHR1, CRH, CRHR2 | CTNNB1 3980/4885WNT3A 3624/4885HTR1B 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.