Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
| ▸ | MTTP | P55157 | 2/20 | 0.46 |
| ▸ | APOB | P04114 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639807 | 0.91 | SMO (0.49) | SMOSORT1MTTPAPOBHTT | |
| SCHEMBL6804592 | 0.90 | SMO (0.64) | SMOMTTPAPOBHTTLMNA | |
| SCHEMBL6644487 | 0.90 | SMO (0.48) | SMOSORT1MTTPAPOBHTT | |
| SCHEMBL6641215 | 0.86 | SMO (0.50) | SMOSORT1MTTPAPOBHTT | |
| SCHEMBL6805454 | 0.82 | SMO (0.60) | SMOMTTPAPOBHTTLMNA | |
| SCHEMBL7084308 | 0.81 | SMO (0.49) | SMOSORT1MTTPAPOBHTT | |
| SCHEMBL7083387 | 0.81 | SMO (0.49) | SMOSORT1HTTLMNARXFP1 | |
| SCHEMBL7086991 | 0.80 | SMO (0.48) | SMOSORT1MTTPAPOBBRAF | |
| SCHEMBL7176879 | 0.79 | SMO (0.42) | SMOABL1KDR | |
| SCHEMBL6641308 | 0.78 | PKM (0.51) | SMOSORT1HTTLMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |