Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795353 | 0.91 | SMO (0.60) | SMOALDH1A1LMNAMAPTGRM4 | |
| SCHEMBL7084308 | 0.90 | SMO (0.49) | SMORXFP1ALDH1A1MEN1LMNA | |
| SCHEMBL6639807 | 0.90 | SMO (0.49) | SMORXFP1ALDH1A1MEN1LMNA | |
| SCHEMBL7079800 | 0.87 | ALDH1A1 (0.47) | SMORXFP1ALDH1A1MEN1LMNA | |
| SCHEMBL6641308 | 0.87 | PKM (0.51) | SMORXFP1ALDH1A1MEN1LMNA | |
| SCHEMBL7083654 | 0.85 | SORT1 (0.45) | SMORXFP1ALDH1A1MEN1LMNA | |
| SCHEMBL6644487 | 0.85 | SMO (0.48) | SMORXFP1ALDH1A1MEN1LMNA | |
| SCHEMBL6492656 | 0.83 | SMO (0.53) | SMOHPGDNR3C1 | |
| SCHEMBL6643055 | 0.82 | SMO (0.46) | SMORXFP1ALDH1A1MEN1LMNA | |
| SCHEMBL6638865 | 0.81 | SMO (0.53) | SMORXFP1ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |