Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | METAP1 | P53582 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636158 | 0.84 | PKM (0.52) | RAB9ANPC1METAP1PRKAB2PRKAG1 | |
| SCHEMBL10733599 | 0.79 | RAB9A (0.51) | RAB9ANPC1METAP1ALDH1A1PRKAB2 | |
| SCHEMBL6638569 | 0.79 | RAB9A (0.51) | RAB9ANPC1METAP1ALDH1A1PRKAB2 | |
| SCHEMBL1042193 | 0.79 | RAB9A (0.54) | RAB9ANPC1METAP1ALDH1A1PRKAB2 | |
| SCHEMBL1078698 | 0.79 | RAB9A (0.54) | RAB9ANPC1METAP1ALDH1A1PRKAB2 | |
| SCHEMBL3601165 | 0.79 | RAB9A (0.54) | RAB9ANPC1METAP1ALDH1A1PRKAB2 | |
| SCHEMBL5093662 | 0.79 | RAB9A (0.54) | RAB9ANPC1METAP1ALDH1A1PRKAB2 | |
| SCHEMBL8348152 | 0.78 | RAB9A (0.50) | RAB9ANPC1METAP1ALDH1A1PRKAB2 | |
| SCHEMBL11935676 | 0.77 | RAB9A (0.49) | RAB9ANPC1METAP1ALDH1A1PRKAB2 | |
| SCHEMBL13233294 | 0.76 | RAB9A (0.51) | RAB9ANPC1METAP1ALDH1A1PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087963-B1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORP (US) | 2004-08-25 | — | — | EP | disclosed |