Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11935676 | 0.98 | RAB9A (0.49) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL10733599 | 0.95 | RAB9A (0.51) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL5093662 | 0.89 | RAB9A (0.54) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL13617157 | 0.80 | RAB9A (0.49) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6638569 | 0.79 | RAB9A (0.51) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1042193 | 0.79 | RAB9A (0.54) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1078698 | 0.79 | RAB9A (0.54) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL3601165 | 0.79 | RAB9A (0.54) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6639726 | 0.78 | RAB9A (0.61) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6637382 | 0.77 | PRKAB2 (0.56) | RAB9ANPC1PRKAB2PRKAG1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021870-A1 | ERYTHROMYCIN A 11, 12-CARBAMATE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |