SCHEMBL6640147

SCHEMBL6640147

Clc1nsnc1OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPK1 P28482 2/20 0.52
ALOX15 P16050 1/20 0.52
HSD17B10 Q99714 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.44
CNR1 P21554 1/20 0.43
ACHE P22303 1/20 0.43
CNR2 P34972 1/20 0.43
PIN1 Q13526 2/20 0.42
LMNA P02545 2/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
PDE5A O76074 1/20 0.41
DAPK1 P53355 1/20 0.40
SLC6A4 P31645 2/20 0.40
CDC7 O00311 1/20 0.40
DBF4 Q9UBU7 1/20 0.40
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2382830 0.84 MGMT (0.40) TSHRALDH1A1MAPK1ALOX15HSD17B10
SCHEMBL8701110 0.75 HSD17B10 (0.49) TSHRALDH1A1MAPK1ALOX15HSD17B10
SCHEMBL8701413 0.75 ALDH1A1 (0.49) TSHRALDH1A1MAPK1ALOX15HSD17B10
SCHEMBL1970895 0.74 POLB (0.47) TSHRALDH1A1MAPK1L3MBTL1CNR1
SCHEMBL11225394 0.74 L3MBTL1 (0.58) TSHRALDH1A1MAPK1L3MBTL1CNR1
SCHEMBL21841313 0.70 LMNA (0.51) TSHRALDH1A1MAPK1L3MBTL1CNR1
SCHEMBL29481626 0.70 LMNA (0.51) TSHRALDH1A1MAPK1L3MBTL1CNR1
SCHEMBL21497171 0.70 CA12 (0.48) TSHRALDH1A1MAPK1L3MBTL1CNR1
SCHEMBL24215198 0.70 L3MBTL1 (0.53) TSHRALDH1A1MAPK1L3MBTL1CNR1
SCHEMBL8788276 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1328261-C Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2007-07-25 CN disclosed
CN-1636981-A Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2005-07-13 CN disclosed
CN-1204137-C Uracil compound and application thereof SUMITOMO CHEMICAL CO (JP) 2005-06-01 CN disclosed
EP-1122244-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2004-09-29 EP disclosed
US-6537948-B1 Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-25 US disclosed
CN-1316426-A Uracil compound and application thereof SUMITOMO CHEMICAL CO (JP) 2001-10-10 CN disclosed
EP-1122244-A1 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-08 EP disclosed