Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150493 | 0.83 | TLR8 (0.37) | HTTRXFP1HDAC3HDAC4HDAC1 | |
| SCHEMBL6642504 | 0.82 | HDAC4 (0.35) | ALDH1A1HTTKDM4EKMT2AALOX15 | |
| SCHEMBL20865570 | 0.81 | DPP7 (0.32) | KDM4EKMT2AHSD17B10PSMB5MEN1 | |
| SCHEMBL6441603 | 0.80 | HSP90AA1 (0.36) | SHMT2LMNAALDH1A1KDM4EPOLB | |
| SCHEMBL18546822 | 0.79 | EPHX1 (0.38) | ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL22006150 | 0.77 | PSMB5 (0.38) | SHMT2LMNAALDH1A1HTTHSD17B10 | |
| SCHEMBL7095098 | 0.75 | LARS1 (0.32) | LMNAALDH1A1HTTKDM4ENPSR1 | |
| SCHEMBL18166867 | 0.74 | TLR7 (0.35) | LMNAALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL7092075 | 0.73 | PSMB5 (0.32) | LMNAALDH1A1HTTKDM4ENPSR1 | |
| SCHEMBL6924182 | 0.72 | MAOB (0.34) | LMNAALDH1A1PKMHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040112-B1 | IMIDAZONAPHTHYRIDINES AND THEIR USE IN INDUCING CYTOKINE BIOSYNTHESIS | MINNESOTA MINING & MFG (US) | 2004-09-22 | — | — | EP | disclosed |