SCHEMBL7095098

SCHEMBL7095098

CC(C)CC(N)C(=O)NCCn1cnc2c(C(C)CCN)nc3cccnc3c21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LARS1 Q9P2J5 5/20 0.32
PSMB5 P28074 3/20 0.32
MTNR1A P48039 1/20 0.32
PSMB1 P20618 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
GLA P06280 2/20 0.31
GAA P10253 2/20 0.31
MAPT P10636 2/20 0.31
HPGD P15428 2/20 0.31
BLM P54132 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
APAF1 O14727 1/20 0.31
USP2 O75604 1/20 0.31
NSD2 O96028 1/20 0.31
LMNA P02545 1/20 0.31
XBP1 P17861 1/20 0.31
CASP1 P29466 1/20 0.31
HTT P42858 1/20 0.31
CASP7 P55210 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20865570 0.94 DPP7 (0.32) LARS1PSMB5PSMB1KDM4EUSP2
SCHEMBL18214190 0.89 TLR7 (0.42) LARS1KDM4EALDH1A1GLAGAA
SCHEMBL22006150 0.88 PSMB5 (0.38) PSMB5MTNR1APSMB1ALDH1A1GAA
SCHEMBL8150493 0.81 TLR8 (0.37) HTTTLR8
SCHEMBL7092075 0.80 PSMB5 (0.32) PSMB5MTNR1APSMB1KDM4EALDH1A1
SCHEMBL6924182 0.79 MAOB (0.34) KDM4EALDH1A1GLAGAAMAPT
SCHEMBL6441603 0.79 HSP90AA1 (0.36) KDM4EALDH1A1LMNACASP1CASP7
SCHEMBL6642504 0.78 HDAC4 (0.35) KDM4EALDH1A1CASP1HTTCASP7
SCHEMBL18546822 0.77 EPHX1 (0.38) ALDH1A1MAPT
SCHEMBL6640299 0.75 SHMT2 (0.37) PSMB5KDM4EALDH1A1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230390410-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY BIRDIE BIOPHARMACEUTICALS INC (KY) 2023-12-07 US claimed
EP-3902532-A1 IMMUNE MODULATORY COMBINATIONS AND METHODS FOR TREATING CANCERS Birdie Biopharmaceuticals, Inc. (KY) 2021-11-03 EP claimed
WO-2020139618-A1 IMMUNE MODULATORY COMBINATIONS AND METHODS FOR TREATING CANCERS BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2020-07-02 WO claimed
US-20190269790-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY SHANGHAI BIRDIE BIOTECH, INC. (CN) 2019-09-05 US claimed
US-20190016808-A1 ANTI-EGFR COMBINATIONS FOR TREATING TUMORS BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2019-01-17 US claimed
US-20180110874-A1 Compounds and Compositions for Immunotherapy SHANGHAI BIRDIE BIOTECH, INC. (CN) 2018-04-26 US claimed
US-9827329-B2 Compounds and compositions for immunotherapy BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2017-11-28 US claimed
US-20170056391-A1 COMBINATION THERAPY COMPOSITIONS AND METHODS FOR TREATING CANCERS BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2017-03-02 US claimed
US-20170028079-A1 Compounds and Compositions for Treating HER2 Positive Tumors SHANGHAI BIRDIE BIOTECH, INC. (CN) 2017-02-02 US claimed
US-20160375148-A1 Compounds and Compositions for Treating EGFR Expressing Tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2016-12-29 US claimed
EP-4691562-A2 ANTI-PD-L1 COMBINATIONS FOR TREATING TUMORS Birdie Biopharmaceuticals Inc. (KY) 2026-02-11 EP disclosed
EP-4001311-B1 ANTI-PD-L1/PD-1 COMBINATIONS FOR TREATING TUMORS BIRDIE BIOPHARMACEUTICALS INC (KY) 2025-11-05 EP disclosed
US-20230390410-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY BIRDIE BIOPHARMACEUTICALS INC (KY) 2023-12-07 US disclosed
US-11786604-B2 Compounds and compositions for treating HER2 positive tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2023-10-17 US disclosed
US-11786604-B2 Compounds and compositions for treating HER2 positive tumors BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2023-10-17 US disclosed
WO-2016004875-A1 COMBINATION THERAPY COMPOSITIONS AND METHODS FOR TREATING CANCERS SHANGHAI BIRDIE BIOTECH, INC. (CN) 2016-01-14 WO disclosed
WO-2015103990-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING EGFR EXPRESSING TUMORS SHANGHAI BIRDIE BIOTECH, INC. (CN) 2015-07-16 WO disclosed
WO-2015103987-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING HER2 POSITIVE TUMORS SHANGHAI BIRDIE BIOTECH, INC. (CN) 2015-07-16 WO disclosed
WO-2015103989-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY SHANGHAI BIRDIE BIOTECH, INC. (CN) 2015-07-16 WO disclosed
US-20030212093-A1 Viricides, antitumor agents 3M INNOVATIVE PROPERTIES COMPANY 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190269790-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY CD47, CD274, TP53 LARS1 3752/4885PSMB5 1601/4885MTNR1A 3481/4885
US-20180110874-A1 Compounds and Compositions for Immunotherapy CD47, CD274, TP53 LARS1 3752/4885PSMB5 1601/4885MTNR1A 3481/4885
US-20170056391-A1 COMBINATION THERAPY COMPOSITIONS AND METHODS FOR TREATING CANCERS TP53, MCL1, MSH2 LARS1 3925/4885PSMB5 3712/4885MTNR1A 1395/4885
US-20170028079-A1 Compounds and Compositions for Treating HER2 Positive Tumors ERBB2, EGFR, TP53 LARS1 4679/4885PSMB5 1285/4885MTNR1A 1935/4885
US-20160375148-A1 Compounds and Compositions for Treating EGFR Expressing Tumors EGFR, ERBB2, ERBB3 LARS1 4498/4885PSMB5 1292/4885MTNR1A 3130/4885
US-20190016808-A1 ANTI-EGFR COMBINATIONS FOR TREATING TUMORS EGFR, ERBB3, ERBB2 LARS1 4093/4885PSMB5 2391/4885MTNR1A 901/4885
US-11786604-B2 Compounds and compositions for treating HER2 positive tumors ERBB2, EGFR, TP53 LARS1 4757/4885PSMB5 1268/4885MTNR1A 1817/4885
US-20030212093-A1 Viricides, antitumor agents IFNG, IFNAR1, MAVS LARS1 2996/4885PSMB5 3316/4885MTNR1A 2817/4885
US-20230390410-A1 COMPOUNDS AND COMPOSITIONS FOR IMMUNOTHERAPY CD47, CD274, TP53 LARS1 3752/4885PSMB5 1601/4885MTNR1A 3481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.