Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 4/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092075 | 0.80 | PSMB5 (0.32) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7095098 | 0.79 | LARS1 (0.32) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL8150493 | 0.76 | TLR8 (0.37) | HTT | |
| SCHEMBL6441603 | 0.75 | HSP90AA1 (0.36) | MAOBADORA2AADORA3KDM4EALDH1A1 | |
| SCHEMBL6642504 | 0.75 | HDAC4 (0.35) | KDM4EALDH1A1CASP1HTTCASP7 | |
| SCHEMBL6640299 | 0.72 | SHMT2 (0.37) | KDM4EALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL18546822 | 0.72 | EPHX1 (0.38) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3355121 | 0.70 | TLR7 (0.52) | — | |
| SCHEMBL18338721 | 0.68 | TLR7 (0.45) | ADORA2AKDM4ELMNAMEN1KMT2A | |
| SCHEMBL18214190 | 0.68 | TLR7 (0.42) | ADORA2AGSK3BKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514985-B1 | Induce the biosynthesis of cytokines such as interferon and tumor necrosis factor; exhibit antiviral and antitumor properties | 3M INNOVATIVE PROPERTIES COMPANY | 2003-02-04 | — | — | US | disclosed |