Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | ACSL1 | P33121 | 10/20 | 0.51 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.50 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147937 | 1.00 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3ACSL1ACSL3 | |
| SCHEMBL20064351 | 0.86 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL21222044 | 0.86 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL7235082 | 0.85 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL1749499 | 0.82 | ACSL1 (0.56) | SLC6A2SLC6A4SLC6A3ACSL1ACSL3 | |
| SCHEMBL663949 | 0.82 | ALDH1A1 (0.49) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL663950 | 0.82 | ALDH1A1 (0.49) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL26637453 | 0.82 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3ACSL1ACSL3 | |
| SCHEMBL26637455 | 0.82 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3ACSL1ACSL3 | |
| SCHEMBL10185234 | 0.81 | DGAT1 (0.48) | ACSL1KMT2AABL1DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423182-A1 | DIACYLETHYLENEDIAMINE COMPOUND | Astellas Pharma Inc. (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | SLC6A2 428/4885SLC6A4 997/4885SLC6A3 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.