Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6640589 | 0.94 | TDP1 (0.34) | SIRT3TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL6636874 | 0.84 | SMN1; SMN2 (0.33) | TDP1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6640101 | 0.82 | GRIN1 (0.33) | TDP1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14292833 | 0.79 | KDM4E (0.31) | KDM4EALDH1A1HPGD | |
| SCHEMBL6637345 | 0.79 | GAA (0.39) | TDP1KDM4EHPGDTSHRPOLB | |
| SCHEMBL10204421 | 0.79 | KMT2A (0.34) | SMN1; SMN2POLB | |
| SCHEMBL6643127 | 0.79 | — | — | |
| SCHEMBL6637359 | 0.78 | HSD17B10 (0.34) | TDP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL12752165 | 0.78 | KMT2A (0.35) | TDP1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10204337 | 0.78 | IDH1 (0.31) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159271-B1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2004-08-25 | — | — | EP | disclosed |
| US-6713486-B1 | HIGH ACTIVITY AGAINST WILD-TYPE AND MUTANT HIV-1; LOW TOXICITY | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2004-03-30 | — | — | US | disclosed |
| EP-1159271-A4 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2002-06-05 | — | — | EP | disclosed |
| EP-1159271-A1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000051990-A1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2000-09-08 | — | — | WO | disclosed |