Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6640589 | 0.89 | TDP1 (0.34) | SMN1; SMN2LMNAMEN1KMT2ATDP1 | |
| SCHEMBL6640101 | 0.86 | GRIN1 (0.33) | SMN1; SMN2LMNATLR7MEN1KMT2A | |
| SCHEMBL6640392 | 0.84 | ADRA1D (0.33) | SMN1; SMN2LMNATDP1KDM4EALDH1A1 | |
| SCHEMBL6637359 | 0.83 | HSD17B10 (0.34) | MEN1KMT2ATDP1KDM4EALDH1A1 | |
| SCHEMBL6637345 | 0.81 | GAA (0.39) | TLR7MEN1KMT2ATDP1KDM4E | |
| SCHEMBL6087076 | 0.81 | GRIN1 (0.43) | TLR7KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL6087200 | 0.80 | KMT2A (0.34) | SMN1; SMN2LMNAMEN1KMT2ATDP1 | |
| SCHEMBL10264966 | 0.79 | KDM4E (0.32) | KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL14292833 | 0.78 | KDM4E (0.31) | KDM4EALDH1A1HPGD | |
| SCHEMBL14293251 | 0.78 | GRIN1 (0.33) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159271-B1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2004-08-25 | — | — | EP | disclosed |