Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6640101 | 0.89 | GRIN1 (0.33) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6776520 | 0.86 | KDM4E (0.34) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6636874 | 0.83 | SMN1; SMN2 (0.33) | KDM4EALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL6640589 | 0.83 | TDP1 (0.34) | HSD17B10KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6636256 | 0.81 | KDM4E (0.34) | HSD17B10KDM4EALDH1A1 | |
| SCHEMBL6637345 | 0.80 | GAA (0.39) | KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL6087076 | 0.80 | GRIN1 (0.43) | HSD17B10KDM4EALDH1A1MAPK1GRIN1 | |
| SCHEMBL10264966 | 0.79 | KDM4E (0.32) | KDM4EALDH1A1GRIN1GRIN2B | |
| SCHEMBL6640392 | 0.78 | ADRA1D (0.33) | HSD17B10KDM4EALDH1A1TDP1 | |
| SCHEMBL12752189 | 0.77 | ALDH1A1 (0.40) | HSD17B10KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159271-B1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2004-08-25 | — | — | EP | disclosed |
| US-6713486-B1 | HIGH ACTIVITY AGAINST WILD-TYPE AND MUTANT HIV-1; LOW TOXICITY | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2004-03-30 | — | — | US | disclosed |