Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 7/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637359 | 0.89 | HSD17B10 (0.34) | GRIN1GRIN2BMEN1KMT2ATDP1 | |
| SCHEMBL6640589 | 0.88 | TDP1 (0.34) | GRIN1GRIN2BMEN1KMT2ATDP1 | |
| SCHEMBL6636874 | 0.86 | SMN1; SMN2 (0.33) | TLR7GAAMEN1KMT2ATDP1 | |
| SCHEMBL6637345 | 0.85 | GAA (0.39) | TLR7GAAMEN1KMT2ATDP1 | |
| SCHEMBL6634062 | 0.85 | MEN1 (0.32) | MEN1KMT2ATDP1 | |
| SCHEMBL6087076 | 0.84 | GRIN1 (0.43) | GRIN1GRIN2BTLR7KDM4EALDH1A1 | |
| SCHEMBL10264966 | 0.83 | KDM4E (0.32) | GRIN1GRIN2BKDM4EALDH1A1HPGD | |
| SCHEMBL6640392 | 0.82 | ADRA1D (0.33) | TDP1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14292833 | 0.82 | KDM4E (0.31) | GRIN1GRIN2BKDM4EALDH1A1HPGD | |
| SCHEMBL14293251 | 0.82 | GRIN1 (0.33) | GRIN1GRIN2BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159271-B1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2004-08-25 | — | — | EP | disclosed |
| US-6713486-B1 | HIGH ACTIVITY AGAINST WILD-TYPE AND MUTANT HIV-1; LOW TOXICITY | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2004-03-30 | — | — | US | disclosed |