Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4546362 | 0.81 | P2RX3 (0.36) | MCOLN2CYP11B1CYP11B2MALT1CYP17A1 | |
| SCHEMBL21347897 | 0.76 | MCOLN2 (0.36) | MCOLN2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL6643532 | 0.74 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL6644690 | 0.74 | CYP17A1 (0.34) | MCOLN2CYP17A1 | |
| SCHEMBL25463387 | 0.73 | TSHR (0.38) | MCOLN2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL18595099 | 0.73 | TSHR (0.38) | MCOLN2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL6643185 | 0.73 | PDE2A (0.40) | CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL21340203 | 0.72 | MCOLN2 (0.33) | MCOLN2CYP17A1 | |
| SCHEMBL2611027 | 0.71 | GABRA1 (0.33) | CYP11B1CYP11B2MALT1CYP17A1 | |
| SCHEMBL2625489 | 0.71 | CYP11B1 (0.40) | MCOLN2CYP11B1CYP11B2MALT1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806230-B1 | NITROGEN COMPOUNDS SUCH AS N-METHYL-N-(2-METHYL-1-(4-TRIFLUORO METHYLPYRIMIDIN-5-YL)PROPYL)PHENYLACETAMIDE, USED FOR PREFERENTIAL CONTROL OF WEEDS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-10-19 | — | — | US | disclosed |
| EP-1211246-B1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2004-02-25 | — | — | EP | disclosed |
| EP-1211246-A1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-06-05 | — | — | EP | disclosed |