Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | VEGFA | P15692 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SOD1 | P00441 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12378005 | 0.97 | CES2 (0.41) | CA12CA1CA9VEGFAIDO1 | |
| SCHEMBL10715281 | 0.91 | VEGFA (0.46) | CA12CA1CA9VEGFAFFAR4 | |
| SCHEMBL28630155 | 0.84 | LTA4H (0.60) | CA1CYP1A2CYP2A6FFAR4FFAR1 | |
| SCHEMBL13316887 | 0.82 | ALDH1A1 (0.45) | VEGFACES2CES1EPAS1FFAR4 | |
| SCHEMBL921111 | 0.80 | VEGFA (0.37) | VEGFAEPAS1FFAR4FFAR1 | |
| SCHEMBL4046325 | 0.80 | ESR1 (0.64) | CA12CA1CA9VEGFA | |
| SCHEMBL12260896 | 0.80 | VEGFA (0.40) | VEGFAIDO1FFAR4FFAR1 | |
| SCHEMBL9713367 | 0.80 | LTA4H (0.54) | CA12CA1CA9FFAR4 | |
| SCHEMBL8999877 | 0.80 | MEN1 (0.43) | VEGFA | |
| SCHEMBL7074972 | 0.78 | EPAS1 (0.44) | VEGFAEPAS1FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254103-B1 | METHOD OF MAKING 3,5-DIFLUOROANILINE FROM 1,3,5-TRICHLOROBENZENE | BASF CORP (US) | 2004-05-26 | — | — | EP | disclosed |
| US-6127577-A | Method of making 3,5-difluoroaniline from 1,3,5-trichlorobenzene | BASF CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0135938-B1 | PROCESS FOR PRODUCING AROMATIC POLYETHER KETONES AND POLYTHIOETHER KETONES | MITSUBISHI KASEI CORPORATION (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-4707536-A | Catalytic preparation of aromatic polyketone from phosgene and aromatic ether or sulfide | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-11-17 | — | — | US | disclosed |
| US-4661581-A | REACTING AROMATIC ETHERS OR THIOETHERS WITH PHOSGENE IN AN APROTIC SOLVENT WITH GROUP 3 METAL HALIDE CATALYST | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0135938-A2 | Process for producing aromatic polyether ketones and polythioether ketones | MITSUBISHI KASEI CORPORATION (JP) | 1985-04-03 | — | — | EP | disclosed |