Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | P62805 | 1/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635701 | 0.85 | MMP3 (0.74) | ALDH1A1HPGDSMN1; SMN2RAB9AMMP3 | |
| SCHEMBL6633131 | 0.83 | ALDH1A1 (0.82) | ALDH1A1HPGDSMN1; SMN2RAB9AMMP3 | |
| SCHEMBL6640806 | 0.83 | NPC1 (0.62) | ALDH1A1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL13381518 | 0.80 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2RAB9AMMP3 | |
| SCHEMBL9856895 | 0.80 | CDC25B (0.56) | ALDH1A1HPGDSMN1; SMN2MMP3HDAC8 | |
| SCHEMBL6632473 | 0.80 | RAB9A (0.52) | ALDH1A1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL13576562 | 0.80 | DEGS1 (0.75) | ALDH1A1HPGDSMN1; SMN2RAB9AMMP3 | |
| SCHEMBL2614258 | 0.80 | RAB9A (0.64) | SMN1; SMN2RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL5639487 | 0.78 | DEGS1 (0.73) | ALDH1A1RAB9AHDAC3HDAC1HDAC2 | |
| SCHEMBL27641548 | 0.78 | HDAC3 (0.63) | RAB9AHDAC8HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |