Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYB | P10242 | 9/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638623 | 0.88 | MYB (0.60) | MYBPOLBRAB9AHSD17B10SMN1; SMN2 | |
| SCHEMBL6640779 | 0.84 | TUBB4A (0.61) | MYBRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL6641362 | 0.83 | HSD17B10 (0.64) | MYBPOLBRAB9AMAPK1HSD17B10 | |
| SCHEMBL6637807 | 0.82 | MYB (0.44) | MYBPOLBRAB9AMAPK1HSD17B10 | |
| SCHEMBL6640084 | 0.82 | MYB (0.47) | MYBPOLBRAB9ATSHRSMN1; SMN2 | |
| SCHEMBL6639889 | 0.78 | MYB (0.63) | MYBPOLBMAPK1HSD17B10TSHR | |
| SCHEMBL4326091 | 0.72 | ALDH1A1 (0.64) | MYBPOLBRAB9AMAPK1HSD17B10 | |
| SCHEMBL4319317 | 0.72 | TUBB4A (0.71) | MYBTSHRTUBB4ATUBBTUBA3C | |
| SCHEMBL4426407 | 0.72 | TUBB4A (0.71) | MYBPOLBRAB9ATSHRTUBB4A | |
| SCHEMBL4343035 | 0.71 | MYB (0.53) | MYBMAPK1HSD17B10TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230232-B1 | SUBSTITUTED 4H-CHROMENE AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA INC (US) | 2004-02-25 | — | — | EP | claimed |