Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14984444 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNACYP2C9KDM4E | |
| SCHEMBL601321 | 0.88 | CYP2C9 (0.46) | ALDH1A1MAPTLMNACYP2C9KDM4E | |
| SCHEMBL10147935 | 0.87 | CYP2C9 (0.47) | ALDH1A1MAPTLMNACYP2C9DGAT1 | |
| SCHEMBL434495 | 0.87 | CYP2C9 (0.47) | ALDH1A1MAPTLMNACYP2C9DGAT1 | |
| SCHEMBL434494 | 0.87 | CYP2C9 (0.47) | ALDH1A1MAPTLMNACYP2C9DGAT1 | |
| SCHEMBL600642 | 0.86 | CYP2C9 (0.46) | ALDH1A1MAPTLMNACYP2C9DGAT1 | |
| SCHEMBL600641 | 0.86 | CYP2C9 (0.46) | ALDH1A1MAPTLMNACYP2C9DGAT1 | |
| SCHEMBL5531306 | 0.84 | ESR2 (0.53) | ALDH1A1MAPTLMNACYP2C9GPR119 | |
| SCHEMBL25447087 | 0.83 | CYP2C9 (0.45) | ALDH1A1MAPTLMNACYP2C9DGAT1 | |
| SCHEMBL17730783 | 0.82 | CYP2C9 (0.46) | ALDH1A1MAPTLMNACYP2C9DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102405209-A | Diacylethylenediamine compound | ASTELLAS PHARMA INC | 2012-04-04 | — | — | CN | disclosed |
| EP-2423182-A1 | DIACYLETHYLENEDIAMINE COMPOUND | Astellas Pharma Inc. (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046292-A1 | DIACYLETHYLENEDIAMINE COMPOUND | DGAT1, DGAT2, DIMT1 | ALDH1A1 963/4885MAPT 2628/4885LMNA 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.