Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | SRPK1 | Q96SB4 | 5/20 | 0.42 |
| ▸ | MTTP | P55157 | 4/20 | 0.42 |
| ▸ | APOB | P04114 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPC | P11150 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666524 | 0.95 | SMO (0.51) | SMOHTR2AHTR2CHTR2BSRPK1 | |
| SCHEMBL6803431 | 0.92 | SMO (0.60) | SMOMTTPAPOBLMNATP53 | |
| SCHEMBL6666013 | 0.89 | SMO (0.51) | SMOHTR2AHTR2CHTR2BSRPK1 | |
| SCHEMBL6669784 | 0.88 | SMO (0.53) | SMOHTR2AHTR2CHTR2BSRPK1 | |
| SCHEMBL6666569 | 0.88 | SMO (0.44) | SMOHTR2AHTR2CHTR2BSRPK1 | |
| SCHEMBL6799860 | 0.87 | SMO (0.61) | SMOHTR2AHTR2CHTR2BMTTP | |
| SCHEMBL6665241 | 0.85 | SMO (0.52) | SMOHTR2AHTR2CHTR2BMTTP | |
| SCHEMBL6663893 | 0.83 | APOB (0.45) | SMOMTTPAPOBLMNA | |
| SCHEMBL6664848 | 0.83 | HTR2A (0.53) | SMOHTR2AHTR2CHTR2BSRPK1 | |
| SCHEMBL6667139 | 0.82 | SMO (0.52) | SMOMTTPAPOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |