Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 5/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001562 | 0.78 | ALDH1A1 (0.40) | TSHRALDH1A1LMNATDP1POLB | |
| SCHEMBL13619904 | 0.76 | HPGD (0.42) | TSHRALDH1A1LMNATDP1POLB | |
| SCHEMBL30487115 | 0.76 | HPGD (0.42) | TSHRALDH1A1LMNATDP1POLB | |
| SCHEMBL10706767 | 0.74 | ALDH1A1 (0.37) | TSHRALDH1A1LMNATDP1POLB | |
| SCHEMBL11097758 | 0.74 | ALDH1A1 (0.37) | TSHRALDH1A1LMNATDP1POLB | |
| SCHEMBL968908 | 0.74 | LMNA (0.56) | TSHRALDH1A1LMNATDP1POLB | |
| SCHEMBL3347914 | 0.74 | ALDH1A1 (0.46) | TSHRALDH1A1LMNATDP1POLB | |
| Hydrochloric Acid SCHEMBL10917756 | 0.73 | ALDH1A1 (0.44) | TSHRALDH1A1LMNATDP1POLB | |
| SCHEMBL664342 | 0.73 | ALDH1A1 (0.44) | TSHRALDH1A1LMNATDP1POLB | |
| SCHEMBL9165049 | 0.70 | LMNA (0.48) | ALDH1A1LMNAPOLBHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120043692-A1 | NUCLEATING AGENT AND THERMOPLASTIC COMPOSITIONS COMPRISING THE SAME | CONNOR DANIEL M (US) | 2012-02-23 | — | — | US | disclosed |