Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | PGK1 | P00558 | 4/20 | 0.36 |
| ▸ | PGK2 | P07205 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347914 | 0.98 | ALDH1A1 (0.46) | ALDH1A1TDP1LMNATSHRCA2 | |
| Hydrochloric Acid SCHEMBL10917756 | 0.95 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNATSHRCA2 | |
| SCHEMBL968908 | 0.84 | LMNA (0.56) | ALDH1A1TDP1LMNATSHRPGK1 | |
| SCHEMBL12002753 | 0.78 | TDP1 (0.47) | ALDH1A1TDP1LMNATSHRCA2 | |
| SCHEMBL8613678 | 0.78 | HPGD (0.43) | ALDH1A1TDP1LMNATSHRCA2 | |
| SCHEMBL2669738 | 0.78 | CYP3A4 (0.43) | ALDH1A1TDP1LMNATSHRCA2 | |
| SCHEMBL11037804 | 0.78 | TDP1 (0.48) | ALDH1A1TDP1LMNATSHRCA2 | |
| SCHEMBL9001562 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TDP1LMNATSHRPOLB | |
| SCHEMBL13619904 | 0.76 | HPGD (0.42) | ALDH1A1TDP1LMNATSHRPOLB | |
| SCHEMBL30487115 | 0.76 | HPGD (0.42) | ALDH1A1TDP1LMNATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120043692-A1 | NUCLEATING AGENT AND THERMOPLASTIC COMPOSITIONS COMPRISING THE SAME | CONNOR DANIEL M (US) | 2012-02-23 | — | — | US | disclosed |