Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 18/20 | 0.76 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.76 |
| ▸ | DRD2 | P14416 | 1/20 | 0.76 |
| ▸ | ADRA1D | P25100 | 15/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 15/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095946 | 1.00 | ADRA1A (0.76) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6712292 | 0.93 | ADRA1A (0.79) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7091765 | 0.93 | ADRA1A (0.79) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6710975 | 0.93 | ADRA1A (0.79) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7093785 | 0.93 | ADRA1A (0.79) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6718967 | 0.92 | ADRA1A (0.77) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7096683 | 0.92 | ADRA1A (0.77) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL3986844 | 0.92 | ADRA1A (0.90) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6715329 | 0.91 | ADRA1A (0.76) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7092125 | 0.91 | ADRA1A (0.76) | ADRA1AMCHR1DRD2ADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866809-B1 | MODIFIED POLYALKADIENE-CONTAINING COMPOSITIONS | LORD CORP (US) | 2002-03-20 | — | — | EP | claimed |
| EP-0662501-A1 | Polymeric compositions, their preparation and use | GENCORP INC. (US) | 1995-07-12 | — | — | EP | claimed |
| US-5389443-A | Improved elongation, flexibility; for fiber reinforced plastics | GENCORP INC. (US) | 1995-02-14 | — | — | US | claimed |
| US-4535147-A | Phosphazene modified amine terminated polymers and method | THE B. F. GOODRICH COMPANY (US) | 1985-08-13 | — | — | US | claimed |
| US-20040242609-A1 | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-12-02 | — | — | US | disclosed |
| EP-1299362-A4 | SELECTIVE MELANIN CONCENTRATING HORMONE-1 (MCH1) RECEPTOR ANTAGONISTS AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2004064774-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-08-05 | — | — | WO | disclosed |
| US-6720324-B2 | THERAPY FOR EATING DISORDERS, SEXUAL DISORDERS, PSYCHOLOGICAL DISORDERS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-04-13 | — | — | US | disclosed |
| US-20040038855-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2004-02-26 | — | — | US | disclosed |
| US-20030082623-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2003-05-01 | — | — | US | disclosed |
| US-20030077701-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2003-04-24 | — | — | US | disclosed |
| US-20030069261-A1 | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof | H. LUNDBECK A/S (DK) | 2003-04-10 | — | — | US | disclosed |
| US-4533726-A | Polymeric hydrophile from carboxy terminated liquid polymer, diamine and phosphazene | THE B. F. GOODRICH COMPANY (US) | 1985-08-06 | — | — | US | disclosed |
| EP-0121357-A2 | Energy-efficient evaporation process with means for vapor recovery | BEND RESEARCH, INC. (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4466202-A | Energy-efficient evaporation process with means for vapor recovery | BEND RESEARCH, INC. (US) | 1984-08-21 | — | — | US | disclosed |
| US-4255538-A | ADDITION POLYMERS AND POLYETHERS MODIFIED BY UNSATURATED EPOXY COMPOUNDS; HIGH SPEED CURING TO SOLID ELASTOMERS | THE B. F. GOODRICH COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| US-4209632-A | BLOWING AGENTS | UNIROYAL, INC. (US) | 1980-06-24 | — | — | US | disclosed |
| US-4135049-A | SULFONYL CARBAZATES AS BLOWING AGENTS | UNIROYAL, INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4119592-A | Rubbery bladders from epoxy compositions | THE B. F. GOODRICH COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
| US-4025578-A | Elastomeric liquid polymer vulcanizates from epoxy resin, liquid carboxy terminated polymer, dihydric phenol, and an amine | THE B. F. GOODRICH COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082623-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | ADRA1A 224/4885MCHR1 1/4885DRD2 271/4885 |
| US-20040038855-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | ADRA1A 88/4885MCHR1 1/4885DRD2 612/4885 |
| US-20040242609-A1 | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof | MCHR1, MCHR2, MC4R | ADRA1A 161/4885MCHR1 1/4885DRD2 175/4885 |
| US-20030077701-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | ADRA1A 224/4885MCHR1 1/4885DRD2 271/4885 |
| US-20030069261-A1 | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof | MCHR1, MCHR2, MC4R | ADRA1A 161/4885MCHR1 1/4885DRD2 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.