Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 18/20 | 0.79 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.79 |
| ▸ | DRD2 | P14416 | 1/20 | 0.79 |
| ▸ | ADRA1D | P25100 | 15/20 | 0.62 |
| ▸ | ADRA1B | P35368 | 15/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710975 | 1.00 | ADRA1A (0.79) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7091765 | 0.95 | ADRA1A (0.79) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6712292 | 0.95 | ADRA1A (0.79) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6718967 | 0.94 | ADRA1A (0.77) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7096683 | 0.94 | ADRA1A (0.77) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL3986844 | 0.93 | ADRA1A (0.90) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7092125 | 0.93 | ADRA1A (0.76) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6715329 | 0.93 | ADRA1A (0.76) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7095946 | 0.93 | ADRA1A (0.76) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL6644689 | 0.93 | ADRA1A (0.76) | ADRA1AMCHR1DRD2ADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030082623-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | H. LUNDBECK A/S (DK) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082623-A1 | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof | MCHR1, MCHR2, MC1R | ADRA1A 224/4885MCHR1 1/4885DRD2 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.