Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645524 | 0.94 | KIF11 (0.39) | KIF11SLC6A1SLC6A11ALDH1A1GAA | |
| SCHEMBL6642327 | 0.77 | SLC6A11 (0.39) | KIF11SLC6A1SLC6A11ALDH1A1GAA | |
| SCHEMBL8979349 | 0.74 | CYP2C19 (0.35) | KIF11ALDH1A1TSHRKDM4EKCNH2 | |
| SCHEMBL18486308 | 0.69 | KIF11 (0.49) | KIF11SLC6A1SLC6A11ALDH1A1GAA | |
| SCHEMBL6645518 | 0.67 | KIF11 (0.40) | KIF11SLC6A1SLC6A11TSHRPKM | |
| SCHEMBL20744914 | 0.66 | KIF11 (0.38) | KIF11ALDH1A1TSHRSMN1; SMN2KCNH2 | |
| SCHEMBL2837144 | 0.66 | SLC6A11 (0.46) | KIF11SLC6A1SLC6A11KCNH2KMT2A | |
| SCHEMBL13646402 | 0.65 | KIF11 (0.58) | KIF11 | |
| SCHEMBL5598775 | 0.64 | SLC6A11 (0.48) | KIF11SLC6A1SLC6A11ALDH1A1KCNH2 | |
| SCHEMBL2631346 | 0.64 | SLC6A11 (0.43) | KIF11SLC6A1SLC6A11KCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422233-A1 | Chemical copying of connectivity information in branched DNA structures | Von Kiedrowski, Günter (DE) | 2004-05-26 | — | — | EP | disclosed |