Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21351764 | 0.75 | KIF11 (0.37) | CYP2C19ALDH1A1TSHRKDM4EMAPT | |
| SCHEMBL6645524 | 0.74 | KIF11 (0.39) | ALDH1A1TSHRKDM4EKIF11KCNH2 | |
| SCHEMBL6645522 | 0.74 | KIF11 (0.39) | ALDH1A1TSHRKDM4EKIF11KCNH2 | |
| SCHEMBL8672157 | 0.74 | RCE1 (0.39) | CYP2C19TSHRKDM4EMAPTHTT | |
| SCHEMBL8672156 | 0.74 | RCE1 (0.39) | CYP2C19TSHRKDM4EMAPTHTT | |
| SCHEMBL5505473 | 0.74 | CYP2C19 (0.39) | CYP2C19ALDH1A1KDM4EMAPT | |
| SCHEMBL6671853 | 0.71 | KIF11 (0.38) | CYP2C19ALDH1A1TSHRKIF11CYP3A4 | |
| SCHEMBL10446011 | 0.71 | CYP2C19 (0.36) | CYP2C19ALDH1A1KDM4EMAPT | |
| SCHEMBL7514211 | 0.70 | TK1 (0.42) | CYP2C19ALDH1A1TSHRHTTKIF11 | |
| SCHEMBL8502919 | 0.70 | TK1 (0.42) | CYP2C19ALDH1A1TSHRHTTKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710225-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN Biotechnik GmbH (DE) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995032181-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN BIOTECHNIK GMBH (DE) | 1995-11-30 | — | — | WO | disclosed |