Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645697 | 1.00 | LMNA (0.45) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL6654456 | 0.88 | NR4A1 (0.51) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7399817 | 0.87 | RAB9A (0.49) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7404735 | 0.86 | ALDH1A1 (0.50) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL5045569 | 0.86 | LMNA (0.45) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL5177381 | 0.86 | LMNA (0.45) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL5045567 | 0.84 | MAOB (0.45) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL5045565 | 0.84 | MAOB (0.45) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7367834 | 0.82 | RAB9A (0.46) | LMNAKMT2ATDP1SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL15251682 | 0.80 | KMT2A (0.45) | LMNAKMT2ATDP1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448534-A1 | 6-MEMBERED UNSATURATED HETEROCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OFTHE COAGULATION CASCADE | Pharmacia Corporation (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003029224-A1 | 6-MEMBERED UNSATURATED HETEROCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |