Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646675 | 1.00 | GAA (0.46) | GAAL3MBTL1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6648311 | 0.99 | SMN1; SMN2 (0.45) | GAAL3MBTL1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6643967 | 0.94 | GAA (0.51) | GAAL3MBTL1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6644388 | 0.93 | EIF2AK3 (0.46) | SMN1; SMN2ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL6647734 | 0.93 | GAA (0.49) | GAAL3MBTL1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6645538 | 0.92 | ALDH1A1 (0.46) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL6643579 | 0.92 | MAPT (0.45) | SMN1; SMN2POLBMAPTNPC1TP53 | |
| SCHEMBL6647940 | 0.91 | MAPT (0.42) | SMN1; SMN2POLBMAPTNPC1TP53 | |
| SCHEMBL6649892 | 0.91 | MAPT (0.42) | SMN1; SMN2POLBMAPTNPC1TP53 | |
| SCHEMBL6649895 | 0.91 | MAPT (0.42) | SMN1; SMN2POLBMAPTNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | GAA 3155/4885L3MBTL1 1609/4885SMN1; SMN2 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.