Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | EYA2 | O00167 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12085022 | 0.88 | TRPA1 (0.40) | LMNAALOX15BLMPMP22TDP1 | |
| SCHEMBL3749558 | 0.87 | TDP1 (0.41) | LMNAALOX15BLMPMP22TDP1 | |
| SCHEMBL29137898 | 0.84 | TDP1 (0.39) | LMNAALOX15BLMPMP22TDP1 | |
| Hydrochloric Acid SCHEMBL5872402 | 0.84 | TDP1 (0.39) | LMNAALOX15BLMPMP22TDP1 | |
| SCHEMBL233033 | 0.82 | TDP1 (0.55) | LMNAALOX15BLMPMP22TDP1 | |
| SCHEMBL3940285 | 0.82 | TDP1 (0.55) | LMNAALOX15BLMPMP22TDP1 | |
| Acetic Acid SCHEMBL321485 | 0.80 | FFAR3 (0.39) | FFAR3LCKFYNLMNAALOX15 | |
| SCHEMBL1498804 | 0.80 | TDP1 (0.52) | LMNAALOX15BLMPMP22TDP1 | |
| SCHEMBL29344409 | 0.78 | TDP1 (0.43) | LMNAALOX15BLMPMP22TDP1 | |
| SCHEMBL18902827 | 0.77 | CHRM2 (0.39) | LMNAALOX15BLMPMP22TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917989-A | Use of a reversible metal electrodeposited electrolyte with pH-adjustable, dynamic glass element with high opacity and excellent rest stability, and electrolyte useful therefor | 代表内华达大学雷诺分校的内华达高等教育系统董事会 | 2024-04-23 | — | — | CN | claimed |
| CN-112522946-B | Low-temperature scouring and bleaching agent and preparation method and application thereof | 湖南工程学院 | 2022-11-01 | — | — | CN | claimed |
| CN-112522946-A | Low-temperature scouring and bleaching agent and preparation method and application thereof | 湖南工程学院 | 2021-03-19 | — | — | CN | claimed |
| EP-1420831-A1 | LIPID CONSTRUCTS AS THERAPEUTIC AND IMAGING AGENTS | Targesome, Inc. (US) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003011345-A1 | LIPID CONSTRUCTS AS THERAPEUTIC AND IMAGING AGENTS | TARGESOME, INC. (US) | 2003-02-13 | — | — | WO | disclosed |