Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 13/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25699306 | 0.82 | AAK1 (0.53) | AAK1CA1CA2CA7 | |
| SCHEMBL13827740 | 0.82 | CA1 (0.44) | AAK1CA1CA2CA7CYP2D6 | |
| SCHEMBL21019435 | 0.79 | AAK1 (0.41) | AAK1CA1CA2CA7CYP2D6 | |
| SCHEMBL56735 | 0.78 | FPR2 (0.46) | AAK1CA1CA2CA7CYP2D6 | |
| SCHEMBL8981149 | 0.78 | CTSK (0.43) | AAK1CA1CA2CA7CYP2D6 | |
| SCHEMBL3823963 | 0.78 | FPR2 (0.46) | AAK1CA1CA2CA7CYP2D6 | |
| SCHEMBL5422252 | 0.78 | DGAT1 (0.42) | AAK1CA1CA2CA7CYP2D6 | |
| SCHEMBL15241159 | 0.78 | AAK1 (0.50) | AAK1 | |
| SCHEMBL30326251 | 0.78 | AAK1 (0.50) | AAK1 | |
| SCHEMBL3821271 | 0.78 | FPR2 (0.46) | AAK1CA1CA2CA7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474425-A1 | DEAZAPURINES AND USES THEREOF | Eisai Co. Ltd. (JP) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003057696-A1 | DEAZAPURINES AND USES THEREOF | EISAI CO. LTD. (JP) | 2003-07-17 | — | — | WO | disclosed |