Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645235 | 0.85 | GRM4 (0.50) | GRM4ALDH1A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL6644506 | 0.82 | ALDH1A1 (0.46) | GRM4ALDH1A1SMN1; SMN2KDM4ERCE1 | |
| SCHEMBL6646415 | 0.82 | NPC1 (0.50) | GRM4ALDH1A1SMN1; SMN2KDM4ERCE1 | |
| SCHEMBL6644190 | 0.80 | OGA (0.52) | GRM4ALDH1A1SMN1; SMN2KDM4ERCE1 | |
| SCHEMBL6646638 | 0.79 | ALDH1A1 (0.48) | GRM4ALDH1A1SMN1; SMN2KDM4ERCE1 | |
| SCHEMBL6648460 | 0.78 | ALDH1A1 (0.46) | GRM4ALDH1A1SMN1; SMN2KDM4ERCE1 | |
| SCHEMBL6644382 | 0.78 | ALDH1A1 (0.46) | GRM4ALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL6645742 | 0.77 | ALDH1A1 (0.44) | GRM4ALDH1A1SMN1; SMN2KDM4ERCE1 | |
| SCHEMBL6647504 | 0.77 | ALDH1A1 (0.46) | GRM4ALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL6647854 | 0.76 | ALDH1A1 (0.44) | GRM4ALDH1A1SMN1; SMN2KDM4ERCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | GRM4 2152/4885ALDH1A1 2174/4885SMN1; SMN2 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.