SCHEMBL66468

SCHEMBL66468

CC(=O)N(C(C)=O)C(N)(C(C)=O)C(C)=O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12057307 0.65 LMNA (0.33) LMNA
SCHEMBL11516983 0.63
SCHEMBL2514973 0.63
Acetone SCHEMBL14937685 0.63 LMNA (0.50) LMNAALOX15BLMPMP22
SCHEMBL20389 0.63 LMNA (0.43) LMNAALOX15BLMPMP22
SCHEMBL7054206 0.63
SCHEMBL27762151 0.63 LMNA (0.31) LMNA
SCHEMBL1866882 0.60
Hydrogen Peroxide SCHEMBL305245 0.60 FFAR3 (0.43) LMNAALOX15BLMPMP22
SCHEMBL18377327 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 803 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120302487-A1 COMPOSITE REVOLYMER LIMITED (GB) 2012-11-29 US claimed
EP-2494024-A1 COMPOSITE Revolymer Limited (GB) 2012-09-05 EP claimed
US-20120108878-A1 Novel Chemistries, Solutions, and Dispersal Systems for Decontamination of Chemical and Biological Systems ARIES ASSOCIATES, INC. (US) 2012-05-03 US claimed
EP-2358643-A1 NOVEL CHEMISTRIES, SOLUTIONS, AND DISPERSAL SYSTEMS FOR DECONTAMINATION OF CHEMICAL AND BIOLOGICAL SYSTEMS Conrad, Michael J. (US) 2011-08-24 EP claimed
WO-2011051681-A1 COMPOSITE REVOLYMER LIMITED (GB) 2011-05-05 WO claimed
EP-0639639-B2 Detergent compositions comprising percarbonate bleaching agents PROCTER & GAMBLE (US) 2010-07-28 EP claimed
US-20100179368-A1 Novel Chemistries, Solutions, and Dispersal Systems for Decontamination of Chemical and Biological Systems ARIES ASSOCIATES, INC. (US) 2010-07-15 US claimed
WO-2010059459-A1 NOVEL CHEMISTRIES, SOLUTIONS, AND DISPERSAL SYSTEMS FOR DECONTAMINATION OF CHEMICAL AND BIOLOGICAL SYSTEMS ARIES ASSOCIATES, INC. (US) 2010-05-27 WO claimed
US-20100119412-A1 Novel Chemistries, Solutions, and Dispersal Systems for Decontamination of Chemical and Biological Systems ARIES ASSOCIATES, INC. (US) 2010-05-13 US claimed
CN-1273597-A Detergent compositions containing polyethyleneimine for enhanced peroxygen bleach stability UNILEVER PLC (NL) 2000-11-15 CN claimed
US-5705466-A High bulk density granular detergents containing a percarbonate bleach and a powdered silicate THE PROCTER & GAMBLE COMPANY (US) 1998-01-06 US claimed
WO-1995005444-A1 HIGH BULK DENSITY GRANULAR DETERGENTS CONTAINING A PERCARBONATE BLEACH AND A POWDERED SILICATE THE PROCTER & GAMBLE COMPANY (US) 1995-02-23 WO claimed
EP-0639639-A1 Detergent compositions comprising percarbonate bleaching agents THE PROCTER & GAMBLE COMPANY (US) 1995-02-22 EP claimed
EP-0320219-B1 Detergent compositions PROCTER & GAMBLE (US) 1994-03-02 EP claimed
EP-0320219-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1989-06-14 EP claimed
EP-0204116-B1 BLEACHING DETERGENT LIQUORS INCORPORATING NON LINEAR ALIPHATIC PEROXYCARBOXYLIC ACID PRECURSORS AND COMPOSITIONS FOR USE THEREIN THE PROCTER & GAMBLE COMPANY (US) 1989-04-19 EP claimed
EP-0204116-A1 Bleaching detergent liquors incorporating non linear aliphatic peroxycarboxylic acid precursors and compositions for use therein THE PROCTER & GAMBLE COMPANY (US) 1986-12-10 EP claimed
US-4539130-A SULFONATE AND CARBOXYLIC ACID ESTERS, ANHYDRIDES AND IMIDE DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1985-09-03 US claimed
EP-0120591-A1 Detergent ingredients, and their use in cleaning compositions and washing processes THE PROCTER & GAMBLE COMPANY (US) 1984-10-03 EP claimed
US-4321157-A SILICA OR SILICATE, ORGANIC PEROXY ACID BLEACH PRECURSOR, ALIPHATIC ALCOHOL-ALKYLENE OXIDE CONDENSATE NONIONIC SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1982-03-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100179368-A1 Novel Chemistries, Solutions, and Dispersal Systems for Decontamination of Chemical and Biological Systems DDT, DCPS, DIS3 LMNA 3507/4885ALOX15 4731/4885BLM 46/4885
US-20120108878-A1 Novel Chemistries, Solutions, and Dispersal Systems for Decontamination of Chemical and Biological Systems DDT, DCPS, DIS3 LMNA 3507/4885ALOX15 4731/4885BLM 46/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.