Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25973768 | 0.96 | ALDH1A1 (0.47) | CCR6PAX8ALDH1A1KDM4ELMNA | |
| SCHEMBL1896919 | 0.85 | ALDH1A1 (0.49) | CCR6PAX8ALDH1A1KMT2AF13A1 | |
| SCHEMBL12013715 | 0.85 | ALDH1A1 (0.51) | CCR6PAX8ALDH1A1LMNAKMT2A | |
| SCHEMBL19346032 | 0.85 | CCR6 (0.53) | CCR6PAX8ALDH1A1LMNAKMT2A | |
| SCHEMBL7367495 | 0.85 | ALDH1A1 (0.58) | CCR6PAX8ALDH1A1LMNAKMT2A | |
| SCHEMBL389007 | 0.84 | HTT (0.51) | CCR6PAX8ALDH1A1KMT2AF13A1 | |
| SCHEMBL8424282 | 0.84 | CCR6 (0.52) | CCR6PAX8ALDH1A1LMNAKMT2A | |
| SCHEMBL3170360 | 0.84 | CCR6 (0.52) | CCR6PAX8ALDH1A1LMNAKMT2A | |
| SCHEMBL31626045 | 0.84 | CCR6 (0.49) | CCR6PAX8ALDH1A1LMNAKMT2A | |
| SCHEMBL31626225 | 0.84 | CCR6 (0.49) | CCR6PAX8ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474425-A1 | DEAZAPURINES AND USES THEREOF | Eisai Co. Ltd. (JP) | 2004-11-10 | — | — | EP | disclosed |
| WO-2004063336-A2 | USES OF DEAZAPURINES FOR THE TREATMENT OF REPERFUSION INJURIES, OSTEOPOROSIS AND/OR BONE METASTASIS | EISAI CO. LTD. (JP) | 2004-07-29 | — | — | WO | disclosed |
| WO-2003057696-A1 | DEAZAPURINES AND USES THEREOF | EISAI CO. LTD. (JP) | 2003-07-17 | — | — | WO | disclosed |