Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | TGM1 | P22735 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3170360 | 1.00 | CCR6 (0.52) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL19346032 | 0.98 | CCR6 (0.53) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL1897393 | 0.94 | CCR6 (0.51) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL19621560 | 0.88 | CHRNB2 (0.43) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL553299 | 0.88 | ALDH1A1 (0.53) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL392019 | 0.87 | HTT (0.50) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL30805121 | 0.87 | CCR6 (0.48) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL27267384 | 0.87 | CCR6 (0.48) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL28002371 | 0.87 | HTT (0.50) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL12013715 | 0.87 | ALDH1A1 (0.51) | CCR6PAX8ALDH1A1F13A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9085523-B2 | Compound for treating cartilage disorders | ONO PHARMACEUTICAL CO., LTD. (JP) | 2015-07-21 | — | — | US | disclosed |
| US-20140171388-A1 | COMPOUND FOR TREATING CARTILAGE DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-06-19 | — | — | US | disclosed |
| EP-0949238-A1 | SUBSTITUTED PROPIONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171388-A1 | COMPOUND FOR TREATING CARTILAGE DISORDERS | COL2A1, COL1A1, ADAMTS1 | CCR6 377/4885PAX8 551/4885ALDH1A1 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.