Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6674326 | 0.92 | P2RX7 (0.60) | P2RX7CNR2ALDH1A1LMNA | |
| SCHEMBL6651900 | 0.86 | P2RX7 (0.47) | P2RX7CNR2ALDH1A1LMNACNR1 | |
| SCHEMBL6653472 | 0.84 | P2RX7 (0.45) | P2RX7CNR2ALDH1A1LMNACNR1 | |
| SCHEMBL6653481 | 0.83 | P2RX7 (0.45) | P2RX7ALDH1A1LMNA | |
| SCHEMBL6655639 | 0.83 | P2RX7 (0.45) | P2RX7CNR2ALDH1A1LMNACNR1 | |
| SCHEMBL6651560 | 0.82 | P2RX7 (0.43) | P2RX7LMNA | |
| SCHEMBL6694983 | 0.82 | P2RX7 (0.43) | P2RX7 | |
| SCHEMBL6686286 | 0.82 | P2RX7 (0.43) | P2RX7EPHX2 | |
| SCHEMBL6658009 | 0.81 | P2RX7 (0.42) | P2RX7EPHX2 | |
| SCHEMBL6655499 | 0.80 | P2RX7 (0.42) | P2RX7LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490341-A1 | NOVEL ADAMANTANE DERIVATIVES | AstraZeneca AB (SE) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003080579-A1 | NOVEL ADAMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-10-02 | — | — | WO | disclosed |