Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | GPR6 | P46095 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695912 | 0.81 | MAPT (0.62) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL6645388 | 0.80 | ACKR3 (0.53) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL6650696 | 0.80 | MAPT (0.52) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL6646623 | 0.79 | FAAH (0.49) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL6705289 | 0.78 | MAPT (0.56) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL6645352 | 0.77 | MAPT (0.57) | MAPTMAPK1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL6491504 | 0.77 | FAAH (0.49) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL6702452 | 0.77 | FAAH (0.55) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL6646088 | 0.77 | FAAH (0.47) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL6646553 | 0.77 | MAPT (0.56) | MAPTTSHRMAPK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | MAPT 4101/4885TSHR 859/4885MAPK1 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.