Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAF1 | P04049 | 3/20 | 0.56 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416643 | 0.83 | KDM4E (0.81) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9416623 | 0.81 | HTT (0.61) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9080604 | 0.81 | MEN1 (0.60) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9416662 | 0.81 | HTT (0.61) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL10730593 | 0.80 | SMPD1 (0.60) | MEN1KMT2AMTNR1AMTNR1BAPP | |
| SCHEMBL10731769 | 0.80 | MTNR1A (0.64) | MEN1KMT2AKDM4EMTNR1AMTNR1B | |
| SCHEMBL5122218 | 0.80 | TRPM8 (0.61) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL14078347 | 0.80 | TRPM8 (0.69) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL14610517 | 0.79 | TRPM8 (0.68) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL5186458 | 0.79 | MEN1 (0.55) | MEN1KMT2AKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613879-A1 | PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TSUMURA & CO. (JP) | 1994-09-07 | — | — | EP | disclosed |