Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 6/20 | 0.61 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.59 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.59 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.59 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.59 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256125 | 0.87 | PHLPP2 (0.64) | GLO1SENP3SENP2SENP1SUMO2 | |
| SCHEMBL4256120 | 0.87 | PHLPP2 (0.64) | GLO1SENP3SENP2SENP1SUMO2 | |
| SCHEMBL13112902 | 0.82 | PHLPP2 (0.56) | GLO1SENP3SENP2SENP1SUMO2 | |
| SCHEMBL18162857 | 0.82 | KMT2A (0.62) | GLO1PHLPP2ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL12721244 | 0.81 | SENP3 (0.63) | GLO1SENP3SENP2SENP1SUMO2 | |
| SCHEMBL11062285 | 0.81 | GLO1 (0.48) | GLO1PHLPP2ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL9094885 | 0.81 | SENP2 (0.63) | GLO1SENP3SENP2SENP1SUMO2 | |
| SCHEMBL9094890 | 0.81 | SENP2 (0.63) | GLO1SENP3SENP2SENP1SUMO2 | |
| SCHEMBL11062287 | 0.81 | GLO1 (0.48) | GLO1PHLPP2ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL28367923 | 0.80 | SENP2 (0.61) | GLO1SENP3SENP2SENP1SUMO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616750-A | Compounds and process | SMITHKLINE BEECHAM PLC (GB) | 1997-04-01 | — | — | US | claimed |
| EP-0655950-B1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY | SMITHKLINE BEECHAM PLC (GB) | 1996-10-23 | — | — | EP | claimed |
| EP-0655950-A1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY. | SMITHKLINE BEECHAM PLC (GB) | 1995-06-07 | — | — | EP | claimed |
| WO-1994003271-A1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY | SMITHKLINE BEECHAM PLC (GB) | 1994-02-17 | — | — | WO | claimed |
| US-6749674-B2 | USEFUL IN RECORDING FLUIDS ESPECIALLY INK JET PRINTING PROCESSES, AND ALSO AS COLORANTS FOR ELECTROPHOTOGRAPHIC TONERS, POWDER COATINGS AND COLOR FILTERS; IMPROVED SOLUBILITY, COLORFASTNESS AND STORAGE STABILITY | CLARIANT GMBH (DE) | 2004-06-15 | — | — | US | disclosed |
| EP-0741731-B1 | PROCESS FOR EPOXIDISING PROCHIRAL OLEFINS | SMITHKLINE BEECHAM PLC (GB) | 2004-04-07 | — | — | EP | disclosed |
| US-20010027734-A1 | Black trisazo metal complex dyes | CLARIANT GMBH | 2001-10-11 | — | — | US | disclosed |
| US-6211107-B1 | Process for expoxidizing prochiral olefins and a catalyst therefor and intermediates for making the catalyst | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-04-03 | — | — | US | disclosed |
| US-5916975-A | Process for epoxidising prochiral olefins and a catalyst therefor and intermediates for making the catalyst | SMITHKLINE BEECHAM P.L.C. (GB) | 1999-06-29 | — | — | US | disclosed |
| US-5616750-A | Compounds and process | SMITHKLINE BEECHAM PLC (GB) | 1997-04-01 | — | — | US | disclosed |
| EP-0741731-A1 | PROCESS FOR EPOXIDISING PROCHIRAL OLEFINS AND A CATALYST THEREFOR AND INTERMEDIATES FOR MAKING THE CATALYST | SMITHKLINE BEECHAM PLC (GB) | 1996-11-13 | — | — | EP | disclosed |
| EP-0655950-B1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY | SMITHKLINE BEECHAM PLC (GB) | 1996-10-23 | — | — | EP | disclosed |
| WO-1995021172-A1 | PROCESS FOR EPOXIDISING PROCHIRAL OLEFINS AND A CATALYST THEREFOR AND INTERMEDIATES FOR MAKING THE CATALYST | SMITHKLINE BEECHAM P.L.C. (GB) | 1995-08-10 | — | — | WO | disclosed |
| EP-0655950-A1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY. | SMITHKLINE BEECHAM PLC (GB) | 1995-06-07 | — | — | EP | disclosed |
| WO-1994003271-A1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY | SMITHKLINE BEECHAM PLC (GB) | 1994-02-17 | — | — | WO | disclosed |