Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | TMPRSS2 | O15393 | 4/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | MAP3K5 | Q99683 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.42 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643701 | 0.84 | MAPT (0.49) | NPC1RAB9AKCNK3KCNK9 | |
| SCHEMBL29803682 | 0.80 | ESR2 (0.54) | ESR2TMPRSS2NR1H2NPC1RAB9A | |
| SCHEMBL1187860 | 0.80 | ESR2 (0.62) | ESR2TMPRSS2NR1H2NPC1RAB9A | |
| SCHEMBL6646767 | 0.79 | ESR2 (0.55) | ESR2TMPRSS2NR1H2MAP3K5NPC1 | |
| SCHEMBL2056208 | 0.79 | ESR2 (0.76) | ESR2NR1H2NPC1RAB9ANAMPT | |
| SCHEMBL1188505 | 0.79 | ESR2 (0.54) | ESR2TMPRSS2NR1H2MAP3K5NPC1 | |
| SCHEMBL31174284 | 0.78 | ESR2 (0.67) | ESR2TMPRSS2NR1H2NPC1RAB9A | |
| SCHEMBL31174286 | 0.78 | ESR2 (0.67) | ESR2TMPRSS2NR1H2NPC1RAB9A | |
| SCHEMBL24671434 | 0.78 | NAMPT (0.61) | ESR2TMPRSS2NR1H2NPC1RAB9A | |
| SCHEMBL29803581 | 0.78 | NAMPT (0.61) | ESR2TMPRSS2NR1H2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | ESR2 294/4885TMPRSS2 2763/4885NR1H2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.