Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650486 | 0.82 | KMT2A (0.38) | KMT2AMEN1FDPSOPRK1ALDH1A1 | |
| SCHEMBL5600154 | 0.82 | ALDH1A1 (0.48) | KMT2AALDH1A1CA12CA1CA2 | |
| SCHEMBL6653570 | 0.82 | HSP90AA1 (0.46) | KMT2AMEN1FDPSOPRK1ALDH1A1 | |
| SCHEMBL6651515 | 0.76 | KMT2A (0.48) | KMT2AMEN1FDPSOPRK1TRPM5 | |
| SCHEMBL6651627 | 0.73 | KDM4E (0.35) | KMT2AMEN1TRPM5ALDH1A1LMNA | |
| SCHEMBL6651254 | 0.73 | KMT2A (0.42) | KMT2AMEN1FDPSOPRK1ALDH1A1 | |
| SCHEMBL6653862 | 0.72 | CYP1A2 (0.35) | KMT2AMEN1TRPM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL4063363 | 0.72 | FDPS (0.48) | KMT2AMEN1FDPSOPRK1TRPM5 | |
| SCHEMBL6650687 | 0.72 | KMT2A (0.47) | KMT2AMEN1FDPSOPRK1TRPM5 | |
| SCHEMBL6672324 | 0.71 | KDM4E (0.33) | KMT2AMEN1TRPM5ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |