Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6649476 | 1.00 | KMT2A (0.46) | KMT2AALDH1A1KDM4EPOLBMTNR1A | |
| SCHEMBL997223 | 0.89 | KMT2A (0.43) | KMT2AALDH1A1KDM4EPOLBMTNR1A | |
| SCHEMBL997225 | 0.89 | KMT2A (0.43) | KMT2AALDH1A1KDM4EPOLBMTNR1A | |
| SCHEMBL19715986 | 0.73 | — | — | |
| SCHEMBL10141758 | 0.68 | APLNR (0.65) | ALDH1A1POLBMTNR1AMTNR1BTSHR | |
| SCHEMBL14229302 | 0.66 | POLB (0.46) | KMT2AALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL9781377 | 0.66 | ALDH1A1 (0.47) | KMT2AALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL6866453 | 0.66 | APLNR (0.71) | KMT2AALDH1A1POLBTSHRMEN1 | |
| SCHEMBL14521439 | 0.66 | APLNR (0.61) | ALDH1A1POLBMTNR1AMTNR1BTSHR | |
| SCHEMBL14229439 | 0.66 | ALDH1A1 (0.45) | KMT2AALDH1A1KDM4EPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292608-B1 | NOVEL COMPOUNDS OF THE N-ACYLAMINO-AMIDE FAMILY, COMPOSITIONS COMPRISING SAME, AND USES | OREAL (FR) | 2004-07-21 | — | — | EP | disclosed |