Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30695890 | 0.86 | ATM (0.42) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL18894198 | 0.86 | ATM (0.42) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL7029965 | 0.85 | TDP1 (0.41) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL8142285 | 0.84 | TDP1 (0.38) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL18128242 | 0.80 | SMN1; SMN2 (0.38) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL31150399 | 0.79 | TDP1 (0.44) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL521184 | 0.79 | TDP1 (0.44) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL8106861 | 0.79 | ALDH1A1 (0.36) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL7022625 | 0.79 | MMP2 (0.36) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL7022634 | 0.79 | MMP2 (0.36) | TDP1ATMALDH1A1HIF1AHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990639-B1 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL IND CO (JP) | 2004-02-25 | — | — | EP | disclosed |
| US-6162944-A | Process for production of N-cyclopropylanilines and intermediates therefor | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| EP-0990639-A1 | PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED THEREFOR | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2000-04-05 | — | — | EP | disclosed |