Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6649596 | 0.85 | TDP1 (0.42) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL18128242 | 0.84 | SMN1; SMN2 (0.38) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL7022625 | 0.83 | MMP2 (0.36) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL7022634 | 0.83 | MMP2 (0.36) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL10434023 | 0.82 | ATM (0.35) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL10434021 | 0.82 | ATM (0.35) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL25374274 | 0.81 | KMT2A (0.35) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL521184 | 0.81 | TDP1 (0.44) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL31150399 | 0.81 | TDP1 (0.44) | TDP1ATMALDH1A1HIF1AHSPB1 | |
| SCHEMBL8106861 | 0.80 | ALDH1A1 (0.36) | TDP1ATMALDH1A1HIF1AHSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280753-A1 | PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL | Rhodia/Chirex, Inc. (US) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001081286-A1 | PROCESS FOR PREPARATION OF R-1-(ARYLOXY)PROPAN-2-OL | RHODIA/CHIREX, INC. (US) | 2001-11-01 | — | — | WO | disclosed |