Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413447 | 0.78 | MAPT (0.32) | — | |
| SCHEMBL6882418 | 0.78 | ALOX5 (0.41) | ADRA1DPOLB | |
| SCHEMBL7071154 | 0.72 | GSK3B (0.31) | — | |
| SCHEMBL28811183 | 0.71 | — | — | |
| SCHEMBL13919765 | 0.69 | — | — | |
| SCHEMBL27688660 | 0.65 | ADRA1D (0.42) | ADRA1DPOLB | |
| SCHEMBL18003233 | 0.65 | — | — | |
| SCHEMBL964511 | 0.64 | — | — | |
| SCHEMBL1474968 | 0.64 | ADRA1D (0.45) | ADRA1DPOLB | |
| SCHEMBL19219824 | 0.64 | ADRA1D (0.38) | ADRA1DPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406632-A2 | SUBSTITUTED 3-ARYL-5-ARYL- 1,2,4]-OXADIAZOLES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | Cytovia, Inc. (US) | 2004-04-14 | — | — | EP | disclosed |
| WO-2002100826-A2 | SUBSTITUTED 3-ARYL-5-ARYL-[1,2,4]-OXADIAZOLES AND ANALOGS | CYTOVIA, INC. (US) | 2002-12-19 | — | — | WO | disclosed |