Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13251874 | 0.79 | MAPT (0.33) | MAPTALDH1A1HTTKMT2A | |
| SCHEMBL6649724 | 0.78 | ADRA1D (0.37) | — | |
| SCHEMBL6882418 | 0.76 | ALOX5 (0.41) | MAPTALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL6648734 | 0.74 | MAPT (0.31) | MAPTALDH1A1HTTKMT2A | |
| SCHEMBL11321729 | 0.64 | SLC6A3 (0.33) | MAPTALDH1A1HTTKMT2A | |
| SCHEMBL13723850 | 0.64 | — | — | |
| SCHEMBL169402 | 0.64 | ALDH1A1 (0.44) | ALDH1A1KMT2A | |
| SCHEMBL1421971 | 0.63 | — | — | |
| SCHEMBL38142 | 0.63 | ACP3 (0.39) | MAPTALDH1A1KMT2A | |
| SCHEMBL1696274 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265606-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009129109-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-22 | — | — | WO | disclosed |
| EP-1406632-A2 | SUBSTITUTED 3-ARYL-5-ARYL- 1,2,4]-OXADIAZOLES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | Cytovia, Inc. (US) | 2004-04-14 | — | — | EP | disclosed |
| WO-2002100826-A2 | SUBSTITUTED 3-ARYL-5-ARYL-[1,2,4]-OXADIAZOLES AND ANALOGS | CYTOVIA, INC. (US) | 2002-12-19 | — | — | WO | disclosed |