Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 1.00 |
| ▸ | AR | P10275 | 10/20 | 1.00 |
| ▸ | NR3C2 | P08235 | 2/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651912 | 0.88 | PGR (1.00) | PGRARNR3C2NR3C1 | |
| SCHEMBL6650765 | 0.86 | PGR (1.00) | PGRARNR3C2NR3C1 | |
| SCHEMBL6650780 | 0.84 | PGR (1.00) | PGRARNR3C2NR3C1 | |
| SCHEMBL5773659 | 0.83 | PGR (1.00) | PGRARNR3C2NR3C1 | |
| SCHEMBL14139076 | 0.76 | PGR (0.61) | PGRARNR3C2NR3C1 | |
| SCHEMBL14138787 | 0.75 | PGR (0.60) | PGRARNR3C2NR3C1 | |
| SCHEMBL4176699 | 0.75 | NR3C1 (1.00) | PGRARNR3C2NR3C1 | |
| SCHEMBL6648084 | 0.75 | PGR (0.78) | PGRARNR3C2NR3C1 | |
| SCHEMBL4169459 | 0.74 | NR3C1 (0.72) | PGRARNR3C2NR3C1 | |
| SCHEMBL14138797 | 0.74 | PGR (0.59) | PGRARNR3C2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043325-B1 | Steroid receptor modulator compounds and methods | LIGAND PHARM INC (US) | 2004-06-16 | — | — | EP | claimed |
| EP-0800519-A1 | STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996019458-A2 | STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1996-06-27 | — | — | WO | disclosed |